DescriptionReversal of novel oral anticoagulants (NOACS) is going to offer the latest updates in NOACS for cardiologists, emergency medicine specialists, trauma surgeons, internists, nurse practitioners, nurses, physician assistants, and pharmacists. All these practitioners practice in anticoagulation, emergency medicine, or critical care to encounter patients taking NOACs. This program discusses the issues of reversibility of NOACs and the development of new drugs that can accomplish this reversal. The objectives of this program are-
- Apply NOAC reversal agents to patient cases taking the patient history and clinical presentation into account.
- Describe the pharmacodynamics and pharmacokinetics of novel oral anticoagulants (NOACs) with a focus on aspects that impact the reversibility of the drugs.
- Describe the mechanisms of action of novel oral anticoagulants and their reversal agents, including universal and class- or drug-specific reversal agents.
- Identify the indications for administration of NOAC antidotes or reversal agents, and describe situations in which laboratory testing for coagulation is appropriate.